We studied the efficacy of space ultra-low volume treatments of 3 insecticides for the control of the dengue virus vector Aedes aegypti in southern Mexico. Insecticides tested were permethrin (Aqua-Reslin® Super), d-phenothrin (Anvil®), and cyfluthrin (Solfac®), applied at rates of 10.87, 7.68, and 2 g/ha, respectively, by using London Fog®, HP910-PHXL®, or Micro-Gen® pumps mounted on vehicles. Studies included 1) open field penetration tests and 2) house penetration tests. Open field tests indicated that Anvil and Solfac were more effective than Aqua-Reslin Super. In house tests, Anvil yielded the highest mosquito mortalities (≥ 88%) of the three insecticides in the front porch, living room, bedroom, and backyard. Therefore, Anvil proved to be better than other insecticides evaluated to control Ae. aegypti in Chiapas, México.